The largest country in South America by population, size, and economy is Brazil. Brazil occupies 3.3 million square miles and has a population of 190.7 million (2010 data) people. Brazil’s population is roughly four times that of Colombia, the second most populous South American country with 46.3 million people.
In terms of Brazil’s economy, Brazil has a GDP of 2,023.528 billion USD, roughly 6 times larger than that of Argentina, the second largest South American economy.
Also See The Largest